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Pharmacological Chaperones Improve Intra-Domain Stability and Inter-Domain Assembly Via Distinct Binding Sites to Rescue Misfolded CFTR

Baatallah, Nesrine,Elbahnsi, Ahmad,Mornon, Jean-Paul,Chevalier, Benoit,Pranke, Iwona,Servel, Nathalie,Zelli, Renaud,Décout, Jean-Luc,Edelman, Aleksander,Sermet-Gaudelus, Isabelle,Callebaut, Isabelle,Hinzpeter, Alexandre

Cellular and molecular life sciences CMLS（2021）

引用 31|浏览38
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关键词
Chemical chaperone,Cystic fibrosis,Protein folding,Binding site,Molecular dynamics
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