Dosimetric Analysis for Predicting Secondary Lymphedema after Radiation for Head and Neck Cancer

To our knowledge, this is the first investigation of dosimetric parameters associated with SL following H&N RT. Our findings suggest that higher volume of low-mid RT dose within the anterior neck is associated with developing SL. This may be related to circumferential neck dose and/or the role of superficial lymphatics within level VI after H&N RT. These findings warrant prospective validation in a larger cohort, but may be considered in the context of RT treatment planning to minimize SL after RT. (HUM00176639).