Design, Synthesis, and Structure–Activity Relationship Optimization of Pyrazolopyrimidine Amide Inhibitors of Phosphoinositide 3-Kinase Γ (Pi3kγ)
Guillaume Mata,Dillon H. Miles,Samuel L. Drew,Jeremy Fournier,Kenneth Lawson,Artur K. Mailyan,Ehesan U. Sharif,Xuelei Yan,Joel W. Beatty,Jesus Banuelos,Jie Chen,Elaine Ginn,Ada Chen,Kimberline Y. Gerrick,Amber T. Pham,Kent Wong,Divyank Soni,Puja Dhanota,Stefan G. Shaqfeh,Cesar Meleza,Nell Narasappa,Hema Singh,Xiaoning Zhao,Lixia Jin,Ulrike Schindler,Matthew J. Walters,Stephen W. Young,Nigel P. Walker,Manmohan Reddy Leleti, Jay P. Powers,Jenna L. Jeffrey Journal of Medicinal Chemistry(2021)
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