Comparison of the Clinical Features Between Posterior Scleritis with Exudative Retinal Detachment and Vogt–Koyanagi–Harada Disease

Purpose This study aims to analyse the differences in clinical characteristics between VKH disease and PS with exudative retinal detachment (ERD). Methods The medical records of 18 eyes of 12 patients with PS accompanied by ERD and 32 eyes of 16 patients with VKH disease were retrospectively reviewed. Results Single ERD was more common in PS, while hyperreflective dots, multiple ERD, retinal pigment epithelium folds were more common in VKH disease on OCT. Both posterior coat thickness and choroid thickness were higher in VKH eyes. “T” sign was observed in 6 of 18 eyes (33.3%) in the PS group, whereas in none of the eyes of VKH disease. No significant differences were shown in FA imaging between PS and VKH cases. Relapse occurred in 12 eyes (66.7%) in PS group, mainly in the posterior segment, while 6 eyes (18.8%) experienced recurrence in the anterior segment in VKH group. Conclusion There are characteristic differences in multimodal imaging parameters and clinical course between VKH and PS with ERD.