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Discovery of Aficamten (CK-274), a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy

Chihyuan Chuang,Scott Collibee,Luke Ashcraft,Wenyue Wang,Mark Vander Wal,Xiaolin Wang, Darren T. Hwee,Yangsong Wu,Jingying Wang,Eva R. Chin,Peadar Cremin,Jeanelle Zamora,James Hartman,Julia Schaletzky,Eddie Wehri,Laura A. Robertson,Fady Malik,Bradley P. Morgan

JOURNAL OF MEDICINAL CHEMISTRY（2021）

Cited 58|Views32

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aficamten,inhibitor,next-generation

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