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Development of an Intracellular Quantitative Assay to Measure Compound Binding Kinetics

Charles S. Lay,Daniel A. Thomas,John P. Evans,Matthew Campbell, Kristopher Mccombe,Alexander N. Phillipou,Laurie J. Gordon,Emma J. Jones,Kristin Riching, Mahnoor Mahmood,Cassie Messenger,Charlotte E. Carver,Kelly M. Gatfield,Peter D. Craggs

Cell chemical biology（2021）

引用 2|浏览44
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关键词
bromodomain,BRD4,BET proteins,NanoBRET,target engagement,kinetics,kon,koff,residence time,SKR
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