A third booster dose may be necessary to mitigate neutralizing antibody fading after inoculation with two doses of an inactivated SARS-CoV-2 vaccine
JOURNAL OF MEDICAL VIROLOGY(2022)
摘要
Neutralizing antibodies in volunteers who received two doses of an inactivated SARS-CoV-2 vaccine deceased over several months. A three-dose procedure study suggested that the boost conferred by a third dose rescued the waning of neutralizing antibodies after the two doses of the inactivated vaccine. Importantly, a booster dose can also elicit a more robust neutralizing antibody response than the two-dose procedure. This article is protected by copyright. All rights reserved.
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关键词
Disease control,Humoral immunity,Immune responses,SARS coronavirus,Vaccines/Vaccine strains,Virus classification
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