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Characterization of the metabolite of cabozantinib generated from liver microsomes and hepatocytes by ultra-high performance liquid chromatography coupled to quadrupole/orbitrap high resolution mass spectrometry

Jiawei Chang,Hao Chen,Jia Chen,Xuehu Sun,Xuesheng Wu,Lei Liu,Zhouwei Xu, Weidong Chen,Jianlin Zhang,Xingyu Wang,Qingwang Liu

Journal of Pharmaceutical and Biomedical Analysis（2021）

Cited 1|Views41
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Key words
Cabozantinib,Metabolic pathways,Liver microsomes,Hepatocytes,Cytochrome P450
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