The Role of SAXS and Molecular Simulations in 3D Structure Elucidation of a DNA Aptamer Against Lung Cancer

Dmitry Morozov,Vladimir Mironov,Roman V. Moryachkov,Irina A. Shchugoreva,Polina V. Artyushenko,Galina S. Zamay, Olga S. Kolovskaya,Tatiana N. Zamay,Alexey V. Krat,Dmitry S. Molodenskiy,Vladimir N. Zabluda,Dmitry V. Veprintsev,Alexey E. Sokolov,Ruslan A. Zukov,Maxim V. Berezovski,Felix N. Tomilin,Dmitri G. Fedorov,Yuri Alexeev,Anna S. Kichkailo

Molecular Therapy — Nucleic Acids（2021）

引用 14|浏览35

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关键词

aptamer,oligonucleotide,tertiary structure,spatial structure,lung adenocarcinoma,small-angle X-ray scattering,SAXS,molecular dynamics,fragment molecular orbital,molecular simulations

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