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Aurora A Kinase Activation: Different Means to Different Ends

˜The œjournal of cell biology/˜The œJournal of cell biology(2021)

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Abstract
Aurora A is a serine/threonine kinase essential for mitotic entry and spindle assembly. Recent molecular studies have revealed the existence of multiple, distinct mechanisms of Aurora A activation, each occurring at specific subcellular locations, optimized for cellular context, and primed by signaling events including phosphorylation and oxidation.
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