Rapid communication: Insights into the role of extracellular vesicles during Auger radioimmunotherapy.

Jihad Karam,Julie Constanzo,Alexandre Pichard,Laurent Gros,Joël Chopineau,Marie Morille,Jean-Pierre Pouget

International journal of radiation biology（2021）

Cited 6|Views23
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Abstract
This study demonstrates that sEVs could play a role during Auger RIT through bystander effects . No systemic effects were observed , under our experimental conditions. However, X-rays experiments showed that sEVs collection time might be influencing the nature of sEVs, a parameter that should also be investigated during Auger RIT.
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Key words
Auger electrons,Targeted radionuclide therapy,exosomes,extracellular vesicles,radiotherapy
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