Hyperpigmentation of the Hands and Feet Revealing Vitamin B12 Deficiency.

Localized or generalized hyperpigmentation is common in dermatology. The causes are multiple, and most of the time etiologic certitude is difficult. Hyperpigmentation because of nutrient deficiencies, particularly vitamin B12, is rare. This is at times associated with a vegetarian diet. The manifestations revealing such a deficit could be hematologic, neurologic, gastrointestinal, and cutaneous. Cutaneous manifestations are rare and are represented by vitiligo, angular cheilitis, stomatitis, and hyperpigmentation of the skin. We report two cases of hyperpigmentation revealing vitamin B12 deficiency.