An Irf1-Irf4 Toggle-Switch Controls Tolerogenic And Immunogenic Transcriptional Programming In Human Langerhans Cells

James Davies,Andres F Vallejo,Sofia Sirvent,Gemma Porter,Kalum Clayton,Yamkela Qumbelo,Patrick Stumpf,Jonathan West,Clive M Gray,Nyaradzo T L Chigorimbo-Murefu,Ben MacArthur,Marta E Polak

FRONTIERS IN IMMUNOLOGY（2021）

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Langerhans cells, single cell transcriptomics, gene regulatory network, mathematical modelling, adaptive immunity, immunotolerance, immunogenic, transcriptional programming

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