Visible recombinant virus of human enterovirus 71 and application thereof

The invention discloses a visible recombinant virus of human enterovirus 71 and an application thereof. In the invention, firstly a double-stranded DNA molecule is protected, wherein the double-stranded DNA molecule is obtained by inserting a coding gene labeled by a CCPGCC label into a 3C protease coding area of genomic DNA of the human enterovirus 71. The CCPGCC label is a polypeptide fragment represented as the sequence I in the sequence table. An expression kit, a recombinant vector, a transgenic cell line or a recombinant bacterium are all belongs to a scope of protection in the invention. The invention also protects a recombinant virus of the human enterovirus 71, wherein the coding DNA of a genomic RNA of the recombinant virus is represented as the sequence 4 in the sequence table. The visible recombinant virus of the human enterovirus 71 has an excellent application prospect in fundamental research.