Clinical Observation on Treating Knee Osteoarthritis Ofwind-Cold-dampness Type with Duhuojisheng Decoction

Purpose: Through clinical observation to study the clinical efficacy of Duhuojisheng Decoction and glucosamine sulfate in the treatment of wind-cold-dampness knee nosteoarthritis, in order to improve the better treatment of wind-cold-dampness arthralgia knee osteoarthritis; it provides a reliable theoretical basis for the clinical application of Duhuojisheng Decoction. Methods: All the cases included in this study were 60 patients with wind-cold-dampness arthralgia knee osteoarthritis who met the criteria and received complete follow-up in our hospital from February 2019 to February 2020. Among them, there were 28 males and 32 females, ranging in age from 45 to 75 years old. Using SPSS19.0 statistical software, 60 patients with knee osteoarthritis were randomly divided into treatment group (n = 30) and control group (n = 30). The treatment group was treated with Duhuojisheng Decoction combined with functional exercise,one day a dose of water decoction, sooner or later. A course of treatment for two weeks, treatment of two courses. The control group was treated with oral glucosamine sulfate combined with functional exercise, 2 times a day, three times a day. A course of treatment for two weeks, treatment of two courses.The knee joint scores of the two groups were observed and recorded in detail in the first and second course of treatment: VAS score, Lysholm score and WOMAC osteoarthritis index score. The statistical software SPSS19.0 was used to deal with and analyze the data of 60 subjects in clinical experiments. The changes of various observation indexes of the two groups before and after treatment were compared, and the clinical efficacy of the two groups was evaluated. Results: 1.Before and after treatment VAS score(Table 1): two groups before treatment VAS score were statistically analyzed, P > 0.05, the difference was not statistically significant; the treatment of the first course, second courses of treatment group and control group group VAS score and VAS score before and after treatment by statistical analysis (t test) were statistically significant (P < 0.05) that, two groups of drugs on the therapeutic effect of KOA were, but efficacy was significantly better than the control group in the treatment group.2. The two groups before and after treatment of knee joint Lysholm score(Table 2): before treatment, the Lysholm scores of the two groups were statistically analyzed, P >0.05, the difference was not statistically significant; the treatment of the first course, second courses of treatment group and control group before and after each treatment score and scores were compared by statistical analysis (t test) were statistically significant (P < 0.05), two groups of drugs on the treatment effect of KOA were but the efficacy of the treatment group was significantly better than the control group.3. The two groups before and after treatment WOMAC Osteoarthritis Index score (Table 3): two groups before treatment Osteoarthritis Index scores were statistically analyzed,P > 0.05, the difference was not statistically significant; the first course, second courses of treatment group and control group Osteoarthritis Index scores before and after each treatment of osteoarthritis index score comparison treatment the statistical analysis (t test) were statistically significant (P < 0.05), indicating that the two groups of drugs on treatment effect were KOA, but the efficacy of the treatment group was significantly better than the control group. Conclusions: Modified Duhuojisheng Decoction and glucosamine have good clinical effects in treating symptoms and restoring joint function in patients with wind-cold-dampness type KOA. However, the clinical effect of the former is more significant, which can significantly improve the quality of life, reduce the pain and improve the knee joint function of patients. Therefore, this prescription is an effective prescription for clinical treatment of wind-cold-dampness type KOA, this prescription is economical and practical, safe and effective, has a good clinical application value, and is worthy of clinical application.View Large Image Figure ViewerDownload Hi-res image Download (PPT)View Large Image Figure ViewerDownload Hi-res image Download (PPT)