In-vivo observations on a topical spot-on formulation (Dermspot spot-on) for prevention of dermatological disorders in dogs

Veterinary practitioners frequently encounter various types of canine dermatological disorders in their clinical practice. The incidence and prevalence of dermatological disorders vary greatly at different places; however, the treatment of such diseases is costly and usually take weeks to months for complete clinical recovery. Therefore, there is a need to explore every possible aspect and generate preventive strategies. Commercially available formulations containing a complex mixture of components suitable to maintain healthy skin can also be explored while looking for preventive solutions. With a similar view, one commercially available topical spot-on formulation (viz., DermSpot Spot-on by TTK) containing a skin lipid complex, essential fatty acids, an anti-hair fall complex, emollients (including Aloe vera extract), antioxidant and biotin was evaluated in dogs in-vivo to observe its effectiveness in prevention of dermatological disorders. The spot-on formulation effectively prevented development of clinical dermatological disorders up to 30 days when used with a suitable protocol. The present paper highlights different aspects of in-vivo evaluation and a disquisition on composition of the formulation. Similar investigations are encouraged on a larger scale including a greater number of dogs in future.