A phosphoinositide-based model of actin waves in frustrated phagocytosis

•Reviews experimental data of the biochemistry of phagocytosis.•Presents a mechanistic model of the actin waves in frustrated phagocytosis and compares it to previous models of actin waves.•Performs a steady state and bifurcation analysis of the resulting differential equations.•Using simulation of the resulting differential equations makes several predictions that are testable in the lab.