An Efficient Synthesis of 3,4-Dihydro-2(1h)-pyrimidinones from Aldehyde Bisulfite Adducts Using Recyclable Wang Resin Supported Sulfonic Acid Catalyst

An efficient one-pot multicomponent synthesis multicomponent synthesis of 3,4- dihydropyrimidin-2(1H)-ones has been developed from aldehyde bisulfite adducts, ethyl acetoacetate and urea using recyclable polymer-supported sulfonic acid catalyst. This new method provides several advantages over the previous synthesis, including high product yields, commercially viable, minimal workup operations and sustainable chemical practices.