Treatment of recalcitrant facial flat warts with ingenol mebutate gel with excellent results

Facial flat warts are benign skin papillomas caused by human papillomavirus infections. They present as papules with hyperkeratotic surface, than can appear alone or in group. Though flat warts normally have spontaneous remission within 2 years, there is a large proportion of cases that can persist years despite treatment and cause significant psychological distress .