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Safety of Local Anesthesia and Prevalence of Hypersensitivity Reactions in Adult Patients with Clonal Mast Cell Diseases: A Retrospective Single-Center Study

The journal of allergy and clinical immunology In practice(2021)

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Abstract
Local anesthetics (LAs) cause hypersensitivity reactions, including toxicity, vasovagal reactions, and side effects of concomitant epinephrine administration and allergic reactions, in 2.5% to 10% of cases.1,2 The introduction of the amide LA group reduced the number of reactions, but related allergy incidence is unclear, as it ranges from 0% to 5% among different studies.1,2
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Key words
Drug Hypersensitivity,House Dust Mite Allergens
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