COVID‐19‐associated coagulopathy—Hypothesis: Are children protected due to enhanced thrombin inhibition by higher α ₂ ‐Macroglobulin macroglobulin (α2‐M)?

Wolfgang Schramm,Rainer Seitz, Lutz Gürtler

Journal of Thrombosis and Haemostasis（2020）

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摘要

We are overwhelmed by scientific publications on clinical observations, virology and epidemiology of SARS-CoV-2 infections. There is a growing body of evidence that hypercoagulability complicates COVID-19, probably contributing to poor prognosis.

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COVID‐19‐associated coagulopathy—Hypothesis: Are children protected due to enhanced thrombin inhibition by higher α 2 ‐Macroglobulin macroglobulin (α2‐M)?

COVID‐19‐associated coagulopathy—Hypothesis: Are children protected due to enhanced thrombin inhibition by higher α ₂ ‐Macroglobulin macroglobulin (α2‐M)?