Curcumin nasal jelly, as well as preparation method and application thereof

user-5fe1a78c4c775e6ec07359f9(2012)

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摘要
The invention belongs to the technical field of medicinal preparations, and particularly relates to a curcumin nasal jelly. The jelly comprises curcumin or pharmaceutically acceptable salt thereof, a jelly matrix and pharmaceutically acceptable auxiliary materials, wherein the concentration of the curcumin is between 0.1 and 5 percent (w/w), namely every 1g of jelly contains 1 to 50mg of curcumin. The curcumin nasal jelly overcomes the defects of poor absorption and low bioavailability of oral curcumin, has simple preparation process, can prolong the residence time of medicament in the nasal cavity, increase medicament absorption, and increase the amount of the medicament in the central nervous system.
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关键词
Curcumin,Bioavailability,Nasal cavity,Chromatography,Chemistry,Preparation method,Residence time
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