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Soluble Α-Synuclein–antibody Complexes Activate the NLRP3 Inflammasome in Hipsc-Derived Microglia

Dorit Trudler,Kristopher L. Nazor,Yvonne S. Eisele,Titas Grabauskas,Nima Dolatabadi,James Parker,Abdullah Sultan,Zhenyu Zhong,Marshall S. Goodwin,Yona Levites,Todd E. Golde,Jeffery W. Kelly,Michael R. Sierks,Nicholas J. Schork,Michael Karin,Rajesh Ambasudhan,Stuart A. Lipton

Proceedings of the National Academy of Sciences（2021）

引用 86|浏览34
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关键词
neuroinflammation,Parkinson's disease,Lewy body dementia,Alzheimer's disease,antibody therapies
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