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Systematic evaluation of structure?property relationships and pharmacokinetics in 6-(hetero)aryl-substituted matched pair analogs of amiloride and 5-(N,N-hexamethylene)amiloride

Bioorganic & medicinal chemistry(2021)

引用 6|浏览18
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关键词
Amiloride,Urokinase,uPA,Cancer,Metastasis,Antimetastatic,Selective optimization of side activity,SOSA,Lead optimization
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