Antibiofilm, Antioxidant And Larvicidal Activity Of Formulated Nanoemulsion From Ocimum Tenuiflorum

Nano emulsions are nano-sized emulsions, which are made for improving the delivery of active pharmaceutical ingredients. These are the thermodynamically steady isotropic systems where two immiscible liquids are mixed to form a single phase by means of an emulsifying agent, i.e., surfactant and cosurfactant. Oil in water emulsions were prepared by high pressure homogenizer using plant essential oils with water as dispersion medium. In this study, stable nanoemulsion was formulated using Ocimum Tenuiflorum (Tulasi) essential oils. It was characterized in terms of Physical, Thermal and Mechanical stability, Particle size distribution and Zeta potential analysis. Then, the antibiofilm and larvicidal activity of Tulsi essential oil and nanoemulsion was investigated. The formulated nanoemulsion exhibited the highest antioxidant activities compared to plant essential oils. In the present study, an attempt has been made to formulate the stable nanoemulsion from the extracts of Ocimum Tenuiflorum with different concentration and is studied for their potential inhibitory action against mosquitoes and biofilm formation. It can be used for the preparation of antimicrobial paint for preventing walls against biofouling. (c) 2021 Elsevier Ltd. All rights reserved. Selection and peer-review under responsibility of the scientific committee of the International Conference on Advances in Materials Research-2019.