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ClC氯通道与肾脏疾病

INTERNATIONAL JOURNAL OF UROLOGY AND NEPHROLOGY(2007)

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Abstract
ClC(voltage-gated chloride channel)电压门控氯离子通道在细胞兴奋性调节、细胞容积调节和跨上皮物质转运等生理过程的调节中发挥重要作用.本文综述ClC通道的分类、分布、结构和功能以及ClC-K、ClC-5基因突变导致肾脏疾病的发病机制.
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Key words
kidney disease
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