COVID-19-induced toxic epidermal necrolysis

Cutaneous manifestations of COVID-19 are been increasingly reported in the literature. These include rashes with varying morphology including maculopapular, urticarial, chilblain-like, vesicular and livedoid/necrotic lesions1 . To add to this compendium of associations with COVID-19, we would like to report a patient who developed Toxic Epidermal Necrolysis (TEN) following a positive diagnosis of COVID-19. We believe this represents a causal association between COVID-19 and TEN. In early December 2020, a 53-year-old lady with metastatic breast carcinoma was referred to Dermatology with a two-day history of a maculopapular rash. She had been an inpatient on the palliative care ward since October 2020 for management of symptoms related to her bone, brain and liver metastasis.