Amiodarone-induced Thyrotoxicosis Refractory to Medical Therapy: A Case Report

Amiodarone is a potent class III antiarrhythmic drug used for both supra and ventricular tachyarrhythmias. Due to its high iodine content and similar structure to thyroxine (T4) and triiodothyronine (T3), abnormalities in thyroid function are common (hyper/hypothyroidism) in patients taking amiodarone, especially with long term use. We present the case of a patient with amiodarone-induced thyrotoxicosis (AIT), refractory to medical therapy, which required total thyroidectomy for symptomatic control.