PD-1 Blockade Aggravates Epstein–Barr Virus+ Post-Transplant Lymphoproliferative Disorder in Humanized Mice Resulting in Central Nervous System Involvement and CD4+ T Cell Dysregulations
Frontiers in Oncology(2021)
关键词
humanized mice,immuno-oncology,Epstein-Barr Virus (EBV),immune checkpoint inhibition (ICI),post-transplant lymphoproliferative disease (PTLD),lymphoma,PD-1,pembrolizumab
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