Maternal obesity provokes hepatic lipidic modulations in offspring in a sex-dependent manner

Background and Aims: With the increasing prevalence of obesity in women in reproductive age, there is an urgent need to further understand the metabolic impact on the fetus. We aim to characterize the sexual dimorphism in offspring in response to maternal obesity with a special focus on hepatic lipid species and the pathophysiological outcomes. We aim to better understand the mechanisms whereby maternal obesity affects the adiposity and lipid composition differently in female (F) and male (M) offspring.