The correlation between the autotaxin enzyme and pruritus in Egyptian patients suffering from chronic liver disease.
Anti-inflammatory & anti-allergy agents in medicinal chemistry(2021)
Abstract
Serum autotaxin level was elevated in patients with chronic liver diseases with pruritus. Autotaxin enzyme may play a key role in the induction of hepatogenic pruritus. So, autotaxin enzyme inhibitors and lysophosphatidic acid (LPA) receptor blockers could be a future line of treatment of hepatogenic pruritus.
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Key words
Cholestasis,Chronic Liver disease,Cirrhosis,Decompensated,Egypt.
,Pruritus
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