Assessment of Macular Function Following Internal Limiting Membrane Peeling with ILM Blue
Cureus(2020)
摘要
PurposeTo evaluate clinical outcome after surgery of idiopathic epiretinal membranes (ERM) with internal limiting membrane (ILM) peeling using a commercial combination of Brilliant blue G (BBG, 0.25 mg/ml) with 4% polyethylene glycol (PEG). MethodsIt was a prospective, single-center study.Macular surgery was performed due to ERM (n = 18) by two experienced surgeons.Exclusion criteria were secondary ERM, previous retinal surgery and pharmacological treatment.Best-corrected visual acuity (BCVA), optical coherence tomography (OCT), and multifocal ERG (RETIscan) were assessed at baseline and three months after surgery. ResultsThe BCVA improved from baseline 0.4 ± 0.13 logMAR to 0.3 ± 0.2 logMAR after three months (p > 0.05).The mean central foveal thickness was reduced from 407 ± 85 μm to 366 ± 56 μm after three months (p > 0.05).At baseline, the mean P1 amplitude (nV/deg 2 ) was 53.5 ± 32.1 in ring 1 and 35.9 ± 20.1 in ring 2. Three months after surgery the mean P1 amplitude was comparable with 57.2 ± 16.3 in ring 1 and 38.0 ± 11.7 in ring 2 compared with the initial situation (p = 0.22 and p = 0.3, respectively). ConclusionBBG with 4% PEG can be used for ILM peeling in patients with idiopathic epiretinal membranes without any sign of short-term toxicity.
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关键词
ilm blue,ilm peeling,brilliant blue g,epiretinal membrane
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