417 the Influence of Left Atrial and Ventricular Volumes on Exercise Capacity in Endurance Athletes

K. Janssens,L. Wright,D. Mooney, C. Lourenco,R. Climie,A. La Gerche

Heart Lung and Circulation（2020）SCI 4区

Cited 0|Views8

Abstract

“Athlete’s heart” describes a symmetrical enlargement of all four cardiac chambers in response to exercise training. However, the uniformity of chamber dilation and the degree to which each contributes to enhanced fitness has not been interrogated. 214 current and former endurance athletes (75% men), aged 16-80 years, underwent a resting echocardiogram and maximal bicycle cardiopulmonary exercise test. Left ventricular volumes (LVEDV) and left atrial volumes (LAESV) were measured using 3D echocardiography and 2D biplane methods, respectively. LVEDV was significantly related to peak VO2 (r=0.643 p<0.001) whereas there was no association between LAESV and exercise capacity (r=0.013 p=0.844). LA/LV ratio (median 0.54) was negatively related to peak VO2 (r=-0.513, p<0.001). Furthermore, a higher LA/LV ratio was observed in athletes with a history of atrial fibrillation (AF, n=19, 0.86±39) compared to those without AF (0.55±14, p<0.001). Athletic remodelling affects the left atrium and ventricle differently, with the latter increasing proportionately to exercise capacity. On the other hand, left atrial enlargement appears to be somewhat maladaptive, with no influence on exercise capacity and associated with the development of AF. The novel ratio of LA/LV volumes warrants further evaluation as a potential predictor of AF.

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