A Thiamonomethinecyanine Probe for Detection of Pb2+ Based on Transformation from Dimer to Monomer by Aptamer
Chemical Papers（2020）
National Center for Occupational Safety and Health
Abstract
A simple method based on a thiamonomethinecyanine dye (dye2) and duplex DNA system was constructed to detect Pb2+ by UV–Vis spectra. The absorption spectra of dye2 show dimers and monomers peak and the monomer–dimer equilibrium could be regulated with environmental change. Duplex DNA as a template was used to regulate distinct aggregates of cyanine dye in the presence of Pb2+. This system shows a specific absorption signal for Pb2+ detection.
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Key words
Thiamonomethinecyanine dye,Pb2+ detection,Dimers and monomers,Assembly and disassembly,G-quadruplex
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