PURULENT APPENDICULAR PSEUDOMONAS PERITONITIS IN CHILDREN AND OPTIMIZATION OF ITS TREATMENT

Over the past decade (2007-2016), Pseudomonas etiology of acute purulent destructive appendicitis in children of the Central Chernozem region has been detected clinically, intraoperatively and bacteriologically in 4-5 patients per year. Totally, over this decade, Pseudomonas etiology of the disease was found in 44 children of age from 2 years 3 months to 14 years old suffering from purulent perforated peritonitis of appendicular origin. The clinical course of diffuse purulent appendicular Pseudomonas peritonitis turned out to be more severe and dangerous than in similar patients with peritonitis caused by enterobacteria: Escherichiosis, Enterococcal, Enterobacter, etc. Traditional combined treatment of such pediatric patients proved to be inefficient due to the resistance of pseudomonas flora to traditional antibacterial drugs. Combined treatment of studied patients with perforation Pseudomonas peritonitis is successfully supplemented by the newly developed differential anti-pseudomonas therapy. It has been successfully used in such patients to prevent the development of abdominal pseudomonas sepsis and to provide patients with full clinical recovery.