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Omipalisib Inspired Macrocycles As Dual PI3K/mTOR Inhibitors

Rosa M. Alvarez,Ana Belen Garcia,Concepcion Riesco-Fagundo,Jose Martin,Carmen Varela,Antonio Rodriguez Hergueta,Esther Gonzalez Cantalapiedra,Julen Oyarzabal,Bruno Di Geronimo,Milagros Lorenzo,M. Isabel Albarran,Antonio Cebria,David Cebrian,Sonia Martinez-Gonzalez,Carmen Blanco-Aparicio,Joaquin Pastor

European Journal of Medicinal Chemistry（2021）

引用 7|浏览52
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关键词
Dual PI3K/mTOR inhibitors,Anticancer therapies,Macrocycles,Drug-like properties,Selectivity,In vivo PK studies
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