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Cerebrospinal Fluid Penetration and Combination Therapy of Entrectinib for Disseminated ROS1/NTRK-Fusion Positive Pediatric High-Grade Glioma

Lisa Mayr,Armin S. Guntner,Sibylle Madlener,Maria T. Schmook,Andreas Peyrl,Amedeo A. Azizi,Karin Dieckmann,Dominik Reisinger,Natalia M. Stepien,Kathrin Schramm,Anna Laemmerer,David T. W. Jones,Jonas Ecker,Felix Sahm,Till Milde,Kristian W. Pajtler,Mirjam Blattner-Johnson, Miroslav Strbac,Christian Dorfer,Thomas Czech,Dominik Kirchhofer,Lisa Gabler,Walter Berger,Christine Haberler,Leonhard Mullauer,Wolfgang Buchberger,Irene Slavc,Daniela Lotsch-Gojo,Johannes Gojo

Journal of personalized medicine（2020）

Cited 17|Views55
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Key words
NTRK fusion,ROS1 fusion,entrectinib,radiotherapy,CSF penetrance,targeted therapies,trametinib,abemaciclib
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