Novel Tricyclic Pyroglutamide Derivatives As Potent RORγt Inverse Agonists Identified Using a Virtual Screening Approach
Qingjie Liu,Douglas G. Batt,Carolyn A. Weigelt,Shiuhang Yip,Dauh-Rurng Wu,Max Ruzanov,John S. Sack,Jinhong Wang,Melissa Yarde,Sha Li,David J. Shuster,Jenny H. Xie,Tara Sherry,Mary T. Obermeier,Aberra Fura,Kevin Stefanski,Georgia Cornelius,Purnima Khandelwal,Joseph A. Tino,John E. Macor,Luisa Salter-Cid,Rex Denton,Qihong Zhao,T. G. Murali Dhar ACS medicinal chemistry letters(2020)
关键词
ROR gamma t,inverse agonist,pyroglutamide,virtual screening,phosphate prodrug
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