Tumor Reliance on Cytosolic Versus Mitochondrial One-Carbon Flux Depends on Folate Availability.

Won Dong Lee,Anna Chiara Pirona,Boris Sarvin,Alon Stern,Keren Nevo-Dinur,Elazar Besser,Nikita Sarvin,Shoval Lagziel,Dzmitry Mukha,Shachar Raz,Elina Aizenshtein,Tomer Shlomi

Cell Metabolism（2021）

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folate cycle,one-carbon flux,cancer metabolism,serine hydroxymethyltransferase,SHMT,reduced folate carrier,mitochondria,physiologic medium,in vivo,metabolomics,isotope tracing

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