Prophylactic risk-reducing salpingo-oophorectomy in BRCA mutation carriers: what is going on in a region of northern Italy?

Maturitas(2021)

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摘要
•Breast cancer survivors underwent risk-reducing salpingo-oophorectomy at a younger age.•The temporal trend for the age distribution of risk-reducing salpingo-oophorectomy was similar for BRCA1 and BRCA2 mutation carriers.•All diagnoses of ovarian invasive cancer were made for BRCA1 or BRCA-combined subjects.•Abnormal tubal findings were mainly found by pathologists in university hospitals.•In none of the few women who underwent concomitant or subsequent hysterectomies was a primitive uterine endometrioid or serous cancer found.
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关键词
BRCA,Risk-reducing salpingo-oophorectomy,Ovarian cancer,Breast cancer survivor,Hysterectomy,Prophylactic, pathology
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