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Development of a Scalable Synthesis of the Small Molecule TGFβR1 Inhibitor BMS-986260

Muthalagu Vetrichelvan,Souvik Rakshit, Sathishkumar Chandrasekaran, Karthikeyan Chinnakalai,Chetan Padmakar Darne, Dyamanna Doddalingappa,Indasi Gopikumar,Anuradha Gupta,Arun Kumar Gupta,Ananta Karmakar,Thirumalai Lakshminarasimhan,David K. Leahy,Senthil Palani,Vignesh Radhakrishnan,Richard Rampulla,Antony Savarimuthu, Varadharajan Subramanian,Upender Velaparthi,Jayakumar Warrier,Martin D. Eastgate,Robert M. Borzilleri,Arvind Mathur,Rajappa Vaidyanathan

ORGANIC PROCESS RESEARCH & DEVELOPMENT（2020）

Cited 3|Views21
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Key words
TGF beta R1 inhibitor,imidazo[1,2-b]pyridazine,TosMIC,AKTS software,Van Leusen imidazole synthesis
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