Treatment by midodrine (Gutron (R)) for permanent arterial hypotension in a chronic dialyzed patient

Chronic hypotension, although unfrequent in uremic patients on hemodialysis, accentuates the deterioration of patients physical state and thus, their general weil-being. These patients often experience acute intradialytic symptoms and respond very poorly to conventional therapies, Well tolerated, midodrine is a suitable and effective choice as it raises blood pressure significantly through its effect on peripheral alpha-adrenergic receptors. The authors report observing the use of midodrine by a dialysis patient during the longest time period published to date, documented by a pharmacokinetic study, and that confirms the excellent results and proves long term tolerance for that drug.