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Directional Versus Omnidirectional Deep Brain Stimulation: Results of a Multi-Cente Prospective Blinded Crossover Study

Parkinsonism & related disorders (Online)/Parkinsonism & related disorders(2020)

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摘要
Introduction: Published reports on directional DBS have been limited to small single-center investigations. Therapeutic window (TW) has been introduced in DBS to describe the range of stimulation amplitudes achieving symptom relief without side effects. The PROGRESS study evaluated whether directional DBS provides a wider TW in a large prospective trial.
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