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EFFICACY AND SAFETY OF FRONT-LINE TREATMENT WITH IBRUTINIB AND RITUXIMAB IN UNFIT PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA (CLL). FIRST REPORT OF THE GIMEMA LLC1114 STUDY

Haematologica(2019)SCI 1区SCI 2区

Sapienza Univ | Pugliese Ciaccio Hosp | Italian Grp Adult Hematol Dis GIMEMA | Fdn IRCCS Ca Granda Osped Maggiore Policlin | Univ Padua | Osped Cardinal Massaia | SS Antonio & Biagio & Cesare Arrigo Hosp | Univ Torino | Univ Modena & Reggio Emilia | Univ Perugia | Univ Piemonte Orientale | Azienda Osped Univ Citta Salute & Sci | Azienda Osped Bianchi Melacrino Morelli | PO V Fazzi | AOU S Giovanni Battista | CTMO Univ | AUSL IRCCS S Maria Nuova Reggio Emilia | Seragnoli Univ Bologna | Azienda Osped Papardo | Univ Siena | Infermi Hosp | Cosenza Hosp | Azienda Policlin OVE | Fdn Policlin Univ A Gemelli | Fdn IRCCS Policlin San Matteo | Azienda Osped Brotzu | Santa Maria delle Croci Hosp | Univ Bari | St Anna Univ Hosp

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AI Summary is the key point extracted automatically understanding the full text of the paper, including the background, methods, results, conclusions, icons and other key content, so that you can get the outline of the paper at a glance.
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  • Pretraining has recently greatly promoted the development of natural language processing (NLP)
  • We show that M6 outperforms the baselines in multimodal downstream tasks, and the large M6 with 10 parameters can reach a better performance
  • We propose a method called M6 that is able to process information of multiple modalities and perform both single-modal and cross-modal understanding and generation
  • The model is scaled to large model with 10 billion parameters with sophisticated deployment, and the 10 -parameter M6-large is the largest pretrained model in Chinese
  • Experimental results show that our proposed M6 outperforms the baseline in a number of downstream tasks concerning both single modality and multiple modalities We will continue the pretraining of extremely large models by increasing data to explore the limit of its performance
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