Endothelial-Specific Deficiency of Thrombospondin-1 Attenuates Abdominal Aortic Aneurysm Through Modulating Vascular Remodeling

Ting Zhou,Carmel Assa,Amelia Stranz,Binkai Liu,Huan Yang,Christine M. Sorenson,Nader Sheibani,Bo Liu

CIRCULATION（2019）

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摘要

Rationale: Thrombospondin-1 (TSP1) is a matricellular protein with TGFβ dependent and independent functions that has been implicated in various vascular diseases. Our previous work demonstrates tha...

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endothelial-specific

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