Synthesis, Crystal Structure and Biological Activity of N-Cyanosulfoximine Derivative Containing 1,2,3-Thiadiazole

The title compound N-cyanosulfoximine derivative containing 1,2,3-thiadiazole (C6H8N4OS2, M-r= 216.28) has been synthesized using 4-(chloromethyl)-5-methyl-1,2,3-thiadiazole as the starting material, and its structure was characterized by IR, H-1 NMR, FIRMS, elemental analysis and single-crystal X-ray diffraction. The crystal of the title compound belongs to orthorhombic, space group Pna2(1) with a = 14.730(6), b = 5.478(2), c = 22.619(9) angstrom, Z = 8, V = 1825.0(13) angstrom(3), Dc = 1.574 g/cm(3), mu = 0.547 mm(-1), F(000) = 896, R = 0.0767 and wR (I> 2 sigma(I)) = 0.2064. X-ray analysis indicates that in this crystal double enantiomers are found as the basically asymmetrical unit and interactions between S(1)--N(3), S(3)...N(4) and S(3)...N(7) are observed. This kind of interactions extends the molecules into a One-dimensional double chain. The preliminary biological test showed that the title compound had insecticidal activity against Myzus persicae in a certain degree and also presented moderate potential bioactivity against tobacco mosaic virus (TMV).