Design, synthesis, and evaluation of substrate - analogue inhibitors of Trypanosoma cruzi ribose 5-phosphate isomerase type B

Soledad Natalia Gonzalez,Jonathan J. Mills,Dante Maugeri, Christopher Olaya,Breana L. Laguera,Jeffrey R. Enders,Julian Sherman,Ana Rodriguez,Joshua G. Pierce,Juan Jose Cazzulo,Edward L. D'Antonio

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS（2021）

引用 3|浏览25

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关键词

Neglected tropical diseases,Chagas' disease,Trypanosoma cruzi,Amastigote,Trypomastigote,Isomerase,Substrate-analogue inhibitors,Competitive inhibition,Trypsin digestion LC-MS/MS

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