PCR-based Comprehensive Genomic Profiling (PCR-CGP): Feasibility from >20,000 Tumor Tissue Specimens (TTS) and Predicted Impact on Actionable Biomarker Identification Versus Hybrid Capture (H)-CGP and Plasma (P)-CGP.

Dan Rhodes, Daniel H. Hovelson,Jennifer Marie Suga,Daniel M. Anderson,Elizabeth Claire Dees,Han A. Koh,Mark E. Burkard,Jamil Khatri,Malek M. Safa,Marc Ryan Matrana,Eddy Shih-Hsin Yang,Alex R. Menter,Benjamin Marshall Parsons,Jennifer Nadine Slim,Jayson Falkner,Travis Reeder,Hana Vakil,Kat Kwiatkowski,Bryan Johnson,Scott A. Tomlins

Journal of clinical oncology（2020）

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摘要

3574Background: Tissue-based h-CGP is increasingly utilized for treatment selection in patients with advanced solid tumors but has high tumor surface area [TSA] requirements (≥25mm2 for leading com...

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