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Structural Basis for GLP-1 Receptor Activation by LY3502970, an Orally Active Nonpeptide Agonist.

Takahiro Kawai,Bingfa Sun,Hitoshi Yoshino,Dan Feng,Yoshiyuki Suzuki,Masanori Fukazawa,Shunsuke Nagao,David B. Wainscott,Aaron D. Showalter,Brian A. Droz,Tong Sun Kobilka,Matthew P. Coghlan,Francis S. Willard,Yoshiki Kawabe,Brian K. Kobilka,Kyle W. Sloop

Proceedings of the National Academy of Sciences of the United States of America（2020）

Cited 80|Views93
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Key words
LY3502970,OWL833,cryoelectron microscopy,glucagon-like peptide-1 receptor,type 2 diabetes mellitus
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