Successful Treatment of Pediatric Post-Liver Transplant Kaposi`s Sarcoma with Paclitaxel.

BACKGROUND:Kaposi`s sarcoma (KS) is a complication of immunosuppressive therapy for transplant recipients. Unlike adult recipients, KS in pediatric organ transplantation is quite rare. Treatment is usually withdrawal of immunosuppression; non-responders often receive chemotherapy.CASE:We have reported a child with post-liver transplant visceral KS which has progressed despite withdrawal of immunosuppressive therapy, who has been treated with Paclitaxel for three weeks. KS has regressed completely after four cycles of Paclitaxel.CONCLUSION:Paclitaxel should be considered as an effective first line treatment option for patients with posttransplant KS.